Solutions crafted by NextGenRnD

We create unparalleled R&D solutions that are behind the success stories of global open innovation in Health Care and Life Sciences sector. The R&D solutions crafted by NextGenRnD have a positive, lasting impact on the pipeline of technologies developed by the leading biopharmaceutical companies. The antibody drug conjugate technology R&D solution created by the founder of NextGenRnD has been acknowledged by Debiopharm in the press releases associated with diagnostic and therapeutic antibody conjugation and in multidrug linker platform technologies.

The impact of our mRNA delivery platform R&D solution has been acknowledged by the CEO of Debiopharm, Dr. Bertrand Ducrey (video, 02:47–03:44).

Technology Readiness Level scale, TRL-scale, is an industrially applied concept that outlines the R&D steps required to progress from Basic Research to Applied Research and ultimately to Experimental Development. Basic Research maps to TRLs 1-2, Applied Research maps to TRLs 3-5, and Experimental Development starts at TRL 6.

Ready-made Solutions created by NextGenRnD contain a transition from Basic Research to Applied Research, the transition from TRL 2 to TRL 3. Our ready-made solutions are switches enabling Basic Research to Applied Research transition.

NextGenRnD ready-made solution is:

(1) formulated technology concept corresponding to at least TRL 2.

(2) research proposal with: (a) detailed experimental design and approach to solve the specified R&D problem; (b) limitations and experimental plan to address them. These characteristics make the seamless transition to TRL 3 highly likely.

(3) novel and based on experimental evidence but not yet reduced to practice;

(4) interdisciplinary addressing the problem emerged, emerging, or re-emerging at the intersection of Life Sciences and at least one of the following: Chemistry, Physics, Engineering, Design, Food, Agriculture, Animal Health, or Human Health.

Here is an example of a simplified NextGenRnD ready-made solution: Soluble, hydroxypropyl-etherified, β-cyclodextrin (HPβCD) for the removal of phenol group compounds.

Discover NextGenRnD ready-made Solutions

Solution      No.    Labels
Next Generation Controlled Release Fertilizer (NextGenCRF)       19    Controlled Release Fertilizer, Biodegradable, Engineering
Universal Pipeline for the Extraction of Nucleic Acids, Polysaccharides, and Proteins from Spent Microbial Biomass       17    Fermentation waste, Spent Microbial Biomass, Valorization, Extraction, Nucleic Acids, Proteins, Polysaccharides, Process Engineering, Aquaculture Health, Animal Health, Human Health
RNA Interference Aided Long-Term Culture of Dirofilaria immitis Third Stage Larvae       14    Dog, Heartworm, Dirofilaria immitis, L3 stage, Culturing, Prevention and Control, Rational Design, One Health
Lawsonia intracellularis propagation – a large-scale intracellular pathogen cultivation model       13    Swine, Lawsonia intracellularis, Cultivation, Attenuation, Vaccine, Enteropathy/Ileitis, Prevention and Control, Rational Design, One Health
Systemic therapeutic peptide delivery via gastrointestinal tract       12    Protein Engineering, Gastrointestinal-to-Systemic Delivery, Rational Design, Human Health
Galvanized virus – determine the lipid composition of every virion in a virus sample population       11    Galvanized Virus, Design, Engineering
Protection of thermally sensitive proteins added to poultry and swine feed       10    Animal Feed, Swine, Poultry, Fluidized bed spraying, Encapsulation, Release, One Health
Longitudinal detection and quantification of intrathecally-injected antisense oligonucleotides in brain using intravenously delivered probe       9    ASO detection and quantification in CNS, Design, Engineering, Chemical Biology, Human Health
Next generation muscle targeting platform       8    Antibody Engineering, Phage Display, Targeting Moiety Minimization, Rational Design, Disease Model, Human Health
FREE The Entrepreneur’s Guide to the Programme for Applied Research — Exploiting Patent Information to Boost Return on Investment from Research & Development Projects       6    Analysis report, Programme for Applied Research, The RUP, Rounds I–VI, Rakendusuuringute programm, Voorud I–VI
Novel quantitative, robust and high-throughput assay for monitoring tau protein aggregation       5    Protein Engineering, Biophysics, High-Throughput Screening, Alzheimer's Disease, Tauopathies, Human Health
Novel drug targets for tuberculosis therapy       4    Human Health, Animal Health, Microbiology, Evolutionary Biology, Systems Biology
Gene therapy targeting platform       3    Molecular Virology, Gene Therapy, Antibody Engineering, Nanoparticle Targeting, Human Health
Airway smooth muscle spheroid contraction sensor platform       2    Human Health, Microtissue, Microfluidics, Microscopy, High-Throughput Screening, Molecular Biology, Chemistry, Physics, Mathematics, Design, Engineering
Rapid internalizing antibody identification platform       1    Phage display, Virology, Cell biology, Design, Engineering

What our customers say about our solutions

Thank you for your proposal which has been selected as the best one. The solution proposed will cover and is compatible with all small antibody formats with no anticipated impact on the antigen-binding site.

  • Search & Evaluation and Scientific Innovation Department; Company size: 420+ employees; Headquarters: Switzerland

The solution is very effective under laboratory conditions.

  • R&D Department; Company size: 5000+ employees; Headquarters: USA

We were impressed by the description of the in vitro model and the level of detail provided, including the research plan as well as the underlying expertise.

  • Discovery Research Department; Company size: 50000+ employees; Headquarters: EU

The solution was detailed in the process, modeling and principles of attenuation.

  • External Research and Innovation Department; Company size: 30000+ employees; Headquarters: USA

The solution is very complete and innovative.

  • R&D Department; Company size: 20000+ employees; Headquarters: EU

The solution was extremely detailed and well planned.