NextGenRnD Solutions

NextGenRnD Solutions mapped to TRL scale

R&D steps		TRLs		Descriptions
Tech qualified through successful operations – Proof of Performance		9		Technology has proven successful in its mission operations (full commercial application)
Tech completed through test and demo		8		Technology completed and qualified through test and demonstration (first of the kind commercial system)
Prototype demo in operational environment		7		Integration and demonstration of industrial prototype system in the operational environment (demonstration system)
Prototype demo in relevant environment – Proof of Principle		6		Prototype system scale-up and demonstration of commercial-scale system in the intended environment
Tech validation in relevant environment		5		Testing and validation of discrete technology components' combination in the intended environment – synergy of technology components (prototype)
Tech validation in lab environment		4		Identification and validation of discrete technology components in the laboratory environment
Analytical & experimental Proof of Concept		3		Critical function of technology/application demonstrated through experimentation NextGenRnD ready-made Solution
Tech concept/application formulated		2		Technology concept/application development NextGenRnD ready-made Solution
Basic principles observed		1		Basic principles observed or postulated, no experimental proof or detailed analysis yet exists NextGenRnD ready-made Solution

The NextGenRnD ready-made Solution

The solutions created by NextGenRnD dissolve the boundaries between formulated technology concept and its experimental proof resulting in seamless transition from TRL 1 to TRL 3.

NextGenRnD ready-made Solution is:

1. the formulated technology concept corresponding to at least TRL 2;
2. the research proposal with: (a) detailed experimental design and approach to solve the specified R&D problem; (b) limitations and experimental plan to address them; and (c) feasibility analysis of the approach. These characteristics make the seamless transition to TRL 3 highly likely;
3. novel and based on experimental evidence but not yet reduced to practice;
4. interdisciplinary addressing the problem emerged, emerging, or re-emerging at the intersection of Life Sciences and at least one of the following: Chemistry, Physics, Engineering, Design, Food, Agriculture, Animal Health, or Human Health;
5. available instantly as PDF download.

Discover NextGenRnD ready-made Solutions

Solution		Fee		Branches recombined
Rapid internalizing antibody identification platform		$1500		Phage display, Virology, Cell biology, Design, Engineering
Gene therapy targeting platform		$1500		Molecular Virology, Gene Therapy, Antibody Engineering, Nanoparticle Targeting, Human Health
Galvanized virus – determine the lipid composition of every virion in a virus sample population		$2500		Galvanized Virus, Design, Engineering
Systemic therapeutic peptide delivery via gastrointestinal tract		$2500		Protein Engineering, Gastrointestinal-to-Systemic Delivery, Rational Design, Human Health
Protection of thermally sensitive proteins added to poultry and swine feed		$3000		Animal Feed, Swine, Poultry, Fluidized bed spraying, Encapsulation, Release, One Health
Lawsonia intracellularis propagation – a large-scale intracellular pathogen cultivation model		$3500		Swine, Lawsonia intracellularis, Cultivation, Attenuation, Vaccine, Enteropathy/Ileitis, Prevention and Control, Rational Design, One Health
Novel drug targets for tuberculosis therapy		$4000		Human Health, Animal Health, Microbiology, Evolutionary Biology, Systems Biology
Muscle targeting platform		$4500		Antibody Engineering, Phage Display, Targeting Moiety Minimization, Rational Design, Disease Model, Human Health
Longitudinal detection and quantification of intrathecally-injected antisense oligonucleotides in brain using intravenously delivered probe		$5000		ASO detection and quantification in CNS, Design, Engineering, Chemical Biology, Human Health
Novel quantitative, robust and high-throughput assay for monitoring tau protein aggregation		$6000		Protein Engineering, Biophysics, High-Throughput Screening, Alzheimer's Disease, Tauopathies, Human Health
Airway smooth muscle spheroid contraction sensor platform		$10000		Human Health, Microtissue, Microfluidics, Microscopy, High-Throughput Screening, Molecular Biology, Chemistry, Physics, Mathematics, Design, Engineering
Novel formulation for mRNA vaccines delivery		$10000		Human Health, RNA Vaccine, Vaccine Formulation

What our customers say about our solutions

The solution is very effective under laboratory conditions.

We were impressed by the description of the in vitro model and the level of detail provided, including the research plan as well as the underlying expertise.

The solution was detailed in the process, modeling and principles of attenuation.

The solution is very complete and innovative.

The solution was extremely detailed and well planned.